Imaging Radiobiology Laboratory–

Publications

  • Graves EE, Giaccia AJ.  Imaging Tumoral Hypoxia: Oxygen Concentrations and Beyond.  Oncology 2007, 21:368-378.

  • Graves EE, Quon A, Loo BW.  RT_Image: An Open Source Tool for Investigating PET in Radiation Oncology.  Technology in Cancer Research and Therapy 2007, 6:111-121.

  • Cecic I, Chan D, Sutphin P, Ray P, Gambhir SS, Giaccia A, Graves EE.  Oxygen sensitivity of reporter genes: implications for preclinical imaging of tumor hypoxia.  Molecular Imaging 2007, 6: 219-228.

  • Cheng Z, Zhang L, Graves E, Xiong Z, Dandekar M, Chen X, Gambhir SS.  Small-animal PET of melanocortin 1 receptor expression using a 18F-labeled alpha-melanocyte-stimulating hormone analog. Journal of Nuclear Medicine 2007, 48:987-994.

  • Lee P, Weerasuriya D, Le Q, Lavori PW, Quon A, Hara W, Wakelee H, Graves E, Loo BW.  Metabolic Tumor Burden Predicts for Disease Progression in Lung Cancer.  International Journal of Radiation Oncology Biology Physics 2007, 69: 328-333.

  • Graves EE, Zhou H, Chatterjee R, Keall PJ, Gambhir SS, Contag CH, Boyer AL.  Design and Evaluation of a Variable Aperture Collimator for Conformal Radiotherapy of Small Animals Using a MicroCT Scanner.  Medical Physics 2007, 34: 4359-4367.

  • Le QT, Koong A, Lieskovsky YY, Narasimhan B, Graves E, Pinto H, Brown JM, Spielman D. In vivo(1)H Magnetic Resonance Spectroscopy of Lactate in Patients with Stage IV Head-and-Neck Squamous Cell Carcinoma. International Journal of Radiation Oncology Biology Physics 2008; 71:1151-1157.

  • Bennewith KL, Huang X, Ham CM, Graves EE, Erler JT, Kambham N, Feazell J, Yang GP, Koong A, Giaccia AJ.  The Role of Tumor Cell-Derived Connective Tissue Growth Factor (CTGF/CCN2) in Pancreatic Tumor Growth.  Cancer Research 2009; 69:775-784.

  • Zhou H, Keall PJ, Graves EE.  A Bone Composition Model for Monte Carlo X-Ray Transport Simulations.  Medical Physics 2009; 36:1008-1018.

  • Rodriguez M, Zhou H, Keall P, Graves E.  Commissioning of a Novel MicroCT/RT System for Small Animal Conformal Radiotherapy.  Physics in Medicine and Biology 2009; 54:3727-3740.

  • Minn AY, Schellenberg D, Maxim P, Cox B, Dieterich S, Xing L, Graves E, Goodman K, Chang D, Koong AC.  Pancreatic tumor motion on a single planning 4D-CT does not correlate with intrafraction tumor motion during treatment.  American Journal of Clinical Oncology 2009; 32:364-368.

  • La TH, Filion EJ, Turnbull BB, Chu JN, Lee P, Nguyen K, Maxim P, Loo BW, Quon A, Graves EE, Le QT. Metabolic Tumor Volume Predicts for Recurrence and Death in Head and Neck Cancer. International Journal of Radiation Oncology Biology Physics 2009; 74:1335-1341.

  • Cairns R, Bennewith K, Graves E, Giaccia A, Chang D, Denko N.  Pharmacologically increased tumor hypoxia can be measured by 18F FAZA PET and enhances tumor response to hypoxic cytotoxin PR-104.  Clinical Cancer Research 2009; 15:7170-7174.

  • Bazalova M, Zhou H, Keall PJ, Graves EE.  Kilovoltage beam Monte Carlo dose calculations in sub-millimeter voxels for small animal radiotherapy.  Medical Physics 2009; 36:4991-4999.

  • Motomura AR, Bazalova M, Zhou H, Keall PJ, Graves EE.  Investigation of the effects of treatment planning variables in small animal radiotherapy dose distributions.  Medical Physics 2010; 37:590-599.

  • Zhou H, Xu J, Rodriguez M, van den Haak F, Zhu X, Xian Y, Nelson G, Jogani R, Keall PJ, Graves EE.  Development of a MicroCT-Based Image-Guided 3D Conformal Radiotherapy System for Small Animals.  International Journal of Radiation Oncology Biology Physics 2010; 78:297-305..

  • Graves EE, Vilalta M, Cecic IK, Erler JT, Tran PT, Felsher D, Sayles L, Sweet-Cordero A, Le QT, Giaccia AJ.  Hypoxia in Models of Lung Cancer: Implications for Radiotherapy and Targeted Therapeutics.  Clinical Cancer Research 2010; 16:4843-4852.

  • Schellenberg D, Quon A, Minn YA, Graves EE, Kunz P, Ford JM, Fisher GA, Goodman KA, Koong AC, Chang DT. 18Fluorodoxyglucose-PET is prognostic of progression free and overall survival in locally advanced pancreas cancer treated with stereotactic radiotherapy.  International Journal of Radiation Oncology Biology Physics 2010; 77:1420-1425.

  • Graves EE, Maity A, Le QT.  The tumor microenvironment in NSCLC.  Seminars in Radiation Oncology 2010; 20:156-163.

  • Murphy JD, La TH, Chu K, Quon A, Fischbein NJ, Maxim PG, Graves EE, Loo BW, Le QT.  Post-Radiation Metabolic Tumor Volume Predicts Outcome in Head-and-Neck Cancer.  International Journal of Radiation Oncology Biology Physics (in press).

  • Apte SD, Chin FT, Graves EE.  Molecular Imaging of Hypoxia: Strategies for Probe Design and Application.  Current Organic Synthesis (in press).

  • Chennupati S, Quon A, Kamaya A, Pai RK, La T, Krakow TE, Graves E, Koong A, Chang DT.  Positron Emission Tomography for Predicting Pathologic Response Following Neoadjuvant Chemoradiotherapy for Locally Advanced Rectal Cancer.  American Journal of Clinical Oncology (in press).

  • Kozak M, Murphy J, Schipper ML, Donington JS, Zhou L, Whyte, RI, Shrager JB, Hoang, C, Bazan J, Maxim PG, Graves EE, Diehn M, Hara W, Quon A, Le QT, Wakelee HA, Loo BW.  Tumor Volume as an Imaging-Based Predictor of Outcome in Preoperative Chemoradiotherapy and Surgery for Locally Advanced Non-Small Cell Lung Cancer.  Journal of Thoracic Oncology (in press).

  • Bazalova M, Nelson G, Noll JM, Graves EE.  The Importance of Tissue Segmentation for Dose Calculations for Kilovoltage Radiation Therapy.  Medical Physics (in press).

  • Lee P, Bazan JG, Lavori PW, Weerasuriya DK, Quon A, Le QT, Wakelee HA, Graves EE, Loo BW.  Metabolic Tumor Volume is an Independent Prognostic Factor in Patients Treated Definitively for Non-Small Cell Lung Cancer.  Clinical Lung Cancer (in press).

  • Murphy JD, Chisholm KM, Daly ME, Wiegner EA, Truong D, Iagaru A, Maxim PG, Loo BW, Graves EE, Kaplan MJ, Kong C, Le QT.  Correlation between metabolic tumor volume and pathologic tumor volume in squamous cell carcinoma of the oral cavity.  Radiotherapy and Oncology (in press).

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